Listen to pronunciation. (kuh-KEK-see-uh) Loss of body weight and muscle mass, and weakness that may occur in patients with cancer, AIDS, or other chronic diseases.
In defining these terms further, anorexia describes loss of appetite and/or an aversion to food. The term “cachexia” refers to a loss of body mass, including lean body mass and fat, in the setting of a disease state, in this case cancer.
People with cachexia lose weight and muscle mass. Some people look malnourished. Others appear to be at a normal weight. To be diagnosed with cachexia, you must have lost at least 5 percent of your body weight within the last 12 months or less, and have a known illness or disease.
Weight loss is the hallmark of any progressive acute or chronic disease state. In its extreme form of significant lean body mass (including skeletal muscle) and fat loss, it is referred to as cachexia. It has been known for millennia that muscle and fat wasting leads to poor outcomes including death.
Because ‘fla’ or ‘flah’ is an evolution from the colonial British ‘FLA-uh’, which would be the common pronunciation of many of the British colonials living in British Malaya. I still pronounce ‘flour’ as ‘FLA-uh’, ‘power’ as ‘PAH-uh’ and ‘prayer’ as ‘PRAE-uh’, with a quick gloss over the diphthong.
It is pronounced pneu·mo·no·ul·tra·mi·cro·scop·ic·sil·i·co·vol·ca·no·co·ni·o·sis.
The survival rate of cachexia can vary depending on the cause. Progressive cachexia is often a sign of poor prognosis and a relatively shorter survival time. The amount and rate of weight loss and survival time are directly related to the survival time of the underlying condition in people with HIV, cancer, and more.
Megestrol acetate (MA) is currently used to improve appetite and to increase weight in cancer‐associated anorexia. In 1993, MA was approved by the US Food and Drug Administration for the treatment of anorexia, cachexia or unexplained weight loss in patients with AIDS.
Cachexia occurs in many cancers, usually at the advanced stages of disease. It is most commonly seen in a subset of cancers, led by pancreatic and gastric cancer, but also lung, esophageal, colorectal, and head and neck cancer.
Cachexia, defined by specific weight loss criteria, has a devastating physical and psychological effect on patients and caregivers. It results in a loss of muscle mass, altered body image, and associated decrease in physical functional level; it also often indicates the end of life.
Summary: Have you ever noticed that people have thinner arms and legs as they get older? As we age it becomes harder to keep our muscles healthy. They get smaller, which decreases strength and increases the likelihood of falls and fractures.
Cachexia is a condition that causes extreme weight loss and muscle wasting. It is a symptom of many chronic conditions such as cancer, chronic renal failure, HIV, and multiple sclerosis. Cachexia predominantly affects people in the late stages of serious diseases like cancer, HIV or AIDS, and congestive heart failure.
Cachexia is defined as ongoing weight loss, often with muscle wasting, associated with a long-standing disease. In cachexia, refeeding often does not induce weight gain.
Progestagens, that is, Medroxyprogesterone Acetate (MPA) and Megestrol Acetate (MA) are currently considered the best available treatment option for CACS, and they are approved in Europe for treatment of cancer- and AIDS-related cachexia.
Cancer cachexia is divided into three consecutive clinical stages:10 pre-cachexia, cachexia, and refractory cachexia, though patients may not experience all three stages.
Cancer-cachexia (CC) is a wasting syndrome that occurs in up to 80% of cancer patients. CC is the primary cause of death for 22%–30% of cancer patients,3,4 with incidence predicted to grow in years to come. Despite CC’s widespread implications, it is often poorly diagnosed and often missed completely.
The term muscle atrophy refers to the loss of muscle tissue. Atrophied muscles appear smaller than normal. Lack of physical activity due to an injury or illness, poor nutrition, genetics, and certain medical conditions can all contribute to muscle atrophy. Muscle atrophy can occur after long periods of inactivity.
Muscular dystrophy is a group of inherited diseases characterized by weakness and wasting away of muscle tissue, with or without the breakdown of nerve tissue.
In English, the correct pronunciation of salmon is sam-un. The “l” in salmon is silent. However, in certain dialects and varieties of English salmon is occasionally pronounced with an “l”.
cachexia pronounce british